With other depressant drugs Opioid

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red line represents number of benzodiazepine deaths involved opioids, , purple line represents benzodiazepine deaths did not involve opioids.


the concurrent use of opioids other depressant drugs such benzodiazepines or ethanol increases rates of adverse events , overdose. overdose of opioid alone, combination of opioid , depressant may precipitate respiratory depression leading death. these risks lessened close monitoring physician, may conduct ongoing screening changes in patient behavior , treatment compliance.








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